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2011年1月12日 星期三

The test may predict which pregnant women will have a life threatening condition

Eclampsia-refers to one in ten pregnant women that cause high blood pressure and protein in the urine.

Only a small proportion of women's condition will go to develop life-threatening complications, but all should be monitored closely.

Only treatment is to deliver a baby soon, but doctors are finely balancing act to examine women who must occur at the earliest because they are at risk of complications and safe to carry their baby plan.

Now researchers at the University of British Colombia in Canada have found a collection of measures and tests that could predict one in 100 women with pre-eclampsia which will develop fully rolled eclampsia, where the parent may suffer seizures, coma and fall in to die.

The results shall be published in the Lancet medical journal.

Researchers set out the calculation using the data for the parent characteristics, past medical history present symptoms; cardiovascular signs; the results of the kidneys, and liver blood tests; and studies such as fetal heart rate and the estimated weight, fetal assessment.

They tested the calculation of more than 2 000 women with pre-eclampsia, 13% goes to develop complications. No one died.

Calculation, called fullPIERS identified more than three-quarters of women who have subsequently had events such as high risk, whereas only 16% of the population is incorrectly identified as high risk.

Older tests may have been abandoned in the light of these findings and replaced with more simple, saving money for laboratory costs, said the researchers.

With Dr. Peter von Dadelszen, children & family Institute for research, University of British Colombia, ledger: "fullPIERS model identifies women exposed to an increased risk of adverse results up to 7 days before complications arise, and thus modify directly patients (e.g., the schedule of delivery, place of care), improving the design of clinical trials, and inform the biomedical research with pre-eclampsia.

"Although the formation of the model has not been completed, we hope that the planned external validation (by prospective data collection and use of existing international databases) and implementation of fullPIERS will help to reduce the risk of life-ending change life (e.g. stroke) and life-threatening (e.g. eclampsia) complications which make-eclampsia important. "

In view of the accompanying commentary, Dr. Gary Darmstadt, by Bill and Melinda Gates Foundation, family Health Division, in Seattle, said: "hypertension in pregnancy and eclampsia-challenge the public in public health because of the need for both the protection of mother and baby and to balance the sometimes competing needs to speed up or slow down at the end of pregnancy.

This study mainly focused on maternal results but also has implications for Neonatal health. Hypertension in pregnancy and pre-eclampsia are conditions which require further cooperation between experts on maternal and Neonatal health.

"We hope that these new knowledge will be translated into effective and immediate action and further adapted and validated for use in countries with low income and middle-according to the Court, thus using its greatest benefit to save the lives of mothers and babies."


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2011年1月3日 星期一

Pregnancy test predict risks

Dec. 25: scientists have a life-saving test, can the predictions, what women with high blood pressure in pregnancy will continue to have complications developed. Pre-eclampsia is up to 10 pregnant women, causes high blood pressure and protein in the urine. Only a minority of women with the condition go on to develop life-threatening complications, but all must be closely monitored. The only cure is early to deliver the baby, but doctors have a fine balancing act, to test, what women need be induced early because you sure can carry your baby at risk of complications to term. Now researchers at University of British Columbia in Canada, a collection of measures and testing predictions to have that in 100 women with pre-eclampsia in full blown eclampsia, where can the mother suffering seizures will develop into a coma and die slip found. The results are published in the Lancet medical journal. A calculation on data on the mother formulated researchers characteristics, past medical history available symptoms; Cycle characters; Results of the kidney, blood and liver tests; and fetal assessment tests such as fetal heart rate and estimated weight. Tested the calculation on more than 2,000 women with preeclampsia, from 13 percent went complications develop. No died. The calculation called FullPIERS, more than three-quarters of women, the events as high risk later, had while only 16% of the population was incorrectly identified as high risk identified. Older tests could be compared to these findings abandoned and by easier, save money on laboratory costs, said the researchers are replaced. Co-author Peter Dadelszen, the child and family Research Institute, University of British Columbia, writes: "the FullPIERS model identifies women at increased risk of negative results up to seven days before complications arise and can change this, direct patient care (E.g. timing of delivery, place of care), improve to inform the design of clinical trials and biomedical investigations into pre-eclampsia."Although the model making process is not completed, we hope that the scheduled external validation (through prospective data collection and use of the received international databases) and the implementation of FullPIERS to reduce the risk of life extension change lives (e.g., stroke) and life-threatening helps (E.g. eclampsia) complications, pre-eclampsia make so important. "In an accompanying commentary article Gary Darmstadt by the Bill and Melinda Gates Foundation, family health Division, in Seattle, said:" high blood pressure in pregnancy and pre-eclampsia challenge the public health community because of the need to protect at the same time the mother and the baby and weighing sometimes competing needs to accelerate or decelerate the end of pregnancy. ""This study focuses primarily on maternal results but also affects the neonatal health. High blood pressure in pregnancy and pre-eclampsia... calls for more cooperation between maternal and neonatal health experts. "We hope that this new knowledge... countries in effective use in low-income and middle-income, be translated and thus to its greatest advantage, used to save the lives of mothers and babies."

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