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2011年1月4日 星期二

The deficiencies observed in the study of diabetes related to pregnancy

NEW YORK (Reuters Health) – just over two-thirds of pregnant women have undergone screening tests for gestational diabetes, according to a new analysis of almost one million patients ' records.

About five percent of women who tested positive for pregnancy-related diabetes just one in five were re-examined within six months after birth, Dr. John m. Nakamoto of Quest Diagnostics Nichols Institute in San Juan Capistrano, California, and his colleagues found.

In particular, of the findings, told Reuters Health Nakamoto, given that a recent large study, Hyperglycemia and adverse pregnancy outcome (HAPO) experience shows that even subtle defects in the metabolism of glucose of the mother during pregnancy, led to health problems for mother and baby. Women who have gestational diabetes are also at increased risk for the future development of type 2 diabetes, he adds.

At present, American College of Obstetricians and Gynecologists and the American Diabetes Association recommends that screening pregnant women for gestational diabetes and women who develop diabetes mellitus associated with pregnancy should be tested six to 12 weeks after delivery, babies.

Laboratory now are most commonly used for screening is 100 g oral glucose tolerance test. Woman drinks heavily sweetened beverages, and then its blood is tested; If at least two tests show abnormally high glucose levels, it shall be deemed to have gestational diabetes.

But now is recommended by the International Association of diabetes and pregnancy study groups, on the basis of the results of a study that different HAPO test-75 g oral glucose tolerance--is used instead, with just a single abnormally high blood glucose results indicate pregnancy-related diabetes.

On the basis of the guidelines, noted Nakamoto, about twice as many women shall be deemed to have gestational diabetes, compared with those who are diagnosed with the test, per 100 g.

In their study, Nakamoto and his team looked at Quest Diagnostics testing data for pregnant women 25 to 40 years (younger women are considered to be at low risk for gestational diabetes), including nearly 925,000 women in all old.

According to their report in the journal in obstetrics and gynaecology, 68% (almost 843,000) have passed the oral glucose tolerance test and five per cent had gestational diabetes.

Women 35 to 40 years are almost twice as likely to have gestational diabetes women 18 to 24, until the risk to women, weighing more than 275 pounds is more than triple, to women who weigh 100-124 pounds. Asian women also are almost double the risk of gestational diabetes, compared to white.

Among the more than 23,000 patients tested positive for gestational diabetes and continued to receive laboratory tests of Quest Diagnostics, within six months from the date of their maturity just 19 percent have been tested for the first, diabetes, researchers found.

"Our national basis study shows that pregnancy rates and the first screening of pregnant women are much less than the recommended guidelines from the American College of Obstetricians and Gynecologists and the American Diabetes Association, Nakamoto and his team type. "It is also important to note that the proportion of women with (gestational diabetes mellitus services) diagnosed returning for the first test is extremely low."

United States preventive services task force-the Government agency that issues recommendations on screening tests--currently States that the existing data is not strong enough to recommend all pregnant women receive the survey for gestational diabetes.

But given the recent study, Nakamoto notes, this group, most likely to revise their recommendation. "Now you have the results of the database by very large international research that is conducted over the last few years. These data, I think you really look at what is now add task force for the results of the database to show that he made a difference. "

SOURCE: http://link.reuters.com/quj43r, midwifery and Gynecology, online 20 December 2010.


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